Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lhx3  LIM homeobox protein 3   (Synonyms: Lim3, mLim-3, P-LIM)
Results	Reference
1	J:155074 Agalliu D, Takada S, Agalliu I, McMahon AP, Jessell TM, Motor neurons with axial muscle projections specified by Wnt4/5 signaling. Neuron. 2009 Mar 12;61(5):708-20
1	J:57340 Arber S, Han B, Mendelsohn M, Smith M, Jessell TM, Sockanathan S, Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron. 1999 Aug;23(4):659-74
1	J:272505 Catela C, Correa E, Wen K, Aburas J, Croci L, Consalez GG, Kratsios P, An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development. Neural Dev. 2019 Jan 18;14(1):2
1	J:190166 Chen JA, Wichterle H, Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific dicer inactivation. Front Neurosci. 2012;6:69
1	J:306254 Crane-Smith Z, Schoenebeck J, Graham KA, Devenney PS, Rose L, Ditzell M, Anderson E, Thomson JI, Klenin N, Kurrasch DM, Lettice LA, Hill RE, A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development. Front Cell Dev Biol. 2021;9:595744
1*	J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207
1	J:139297 Dasen JS, De Camilli A, Wang B, Tucker PW, Jessell TM, Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell. 2008 Jul 25;134(2):304-16
1	J:132705 De Marco Garcia NV, Jessell TM, Early motor neuron pool identity and muscle nerve trajectory defined by postmitotic restrictions in Nkx6.1 activity. Neuron. 2008 Jan 24;57(2):217-31
1	J:178688 Demireva EY, Shapiro LS, Jessell TM, Zampieri N, Motor neuron position and topographic order imposed by beta- and gamma-catenin activities. Cell. 2011 Oct 28;147(3):641-52
1	J:271772 Dewitz C, Pimpinella S, Hackel P, Akalin A, Jessell TM, Zampieri N, Nuclear Organization in the Spinal Cord Depends on Motor Neuron Lamination Orchestrated by Catenin and Afadin Function. Cell Rep. 2018 Feb 13;22(7):1681-1694
1*	J:40032 Dou C, Ye X, Stewart C, Lai E, Li SC, TWH regulates the development of subsets of spinal cord neurons. Neuron. 1997 Apr;18(4):539-51
1	J:209344 Dougherty KJ, Zagoraiou L, Satoh D, Rozani I, Doobar S, Arber S, Jessell TM, Kiehn O, Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons. Neuron. 2013 Nov 20;80(4):920-33
1*	J:70423 Eggenschwiler JT, Espinoza E, Anderson KV, Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway. Nature. 2001 Jul 12;412(6843):194-8
1	J:312043 Galdo M, Gregonis J, Fiore CS, Compagnone NA, Dehydroepiandrosterone biosynthesis, role, and mechanism of action in the developing neural tube. Front Endocrinol (Lausanne). 2012;3:16
1	J:231503 Gergics P, Brinkmeier ML, Camper SA, Lhx4 deficiency: increased cyclin-dependent kinase inhibitor expression and pituitary hypoplasia. Mol Endocrinol. 2015 Apr;29(4):597-612
1	J:255024 Hinckley CA, Alaynick WA, Gallarda BW, Hayashi M, Hilde KL, Driscoll SP, Dekker JD, Tucker HO, Sharpee TO, Pfaff SL, Spinal Locomotor Circuits Develop Using Hierarchical Rules Based on Motorneuron Position and Identity. Neuron. 2015 Sep 2;87(5):1008-21
1	J:345795 Hsu HC, Hsu SP, Hsu FY, Chang M, Chen JA, LncRNA Litchi is a regulator for harmonizing maturity and resilient functionality in spinal motor neurons. iScience. 2024 Mar 15;27(3):109207
1	J:112635 Ji SJ, Zhuang B, Falco C, Schneider A, Schuster-Gossler K, Gossler A, Sockanathan S, Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons. Dev Biol. 2006 Sep 1;297(1):249-61
1	J:166088 Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein J, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS, Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron. 2010 Sep 9;67(5):781-96
1	J:332369 Liau ES, Jin S, Chen YC, Liu WS, Calon M, Nedelec S, Nie Q, Chen JA, Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons. Nat Commun. 2023 Jan 3;14(1):46
1	J:277700 Nam H, Jeon S, An H, Yoo J, Lee HJ, Lee SK, Lee S, Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification. Elife. 2019 Jul 15;8:e46683
1	J:193399 Park S, Lee C, Sabharwal P, Zhang M, Meyers CL, Sockanathan S, GDE2 promotes neurogenesis by glycosylphosphatidylinositol-anchor cleavage of RECK. Science. 2013 Jan 18;339(6117):324-8
1	J:143958 Qi Y, Ranish JA, Zhu X, Krones A, Zhang J, Aebersold R, Rose DW, Rosenfeld MG, Carriere C, Atbf1 is required for the Pit1 gene early activation. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2481-6
1	J:178550 Sabharwal P, Lee C, Park S, Rao M, Sockanathan S, GDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signaling. Neuron. 2011 Sep 22;71(6):1058-70
1	J:51420 Sharma K, Sheng HZ, Lettieri K, Li H, Karavanov A, Potter S, Westphal H, Pfaff SL, LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell. 1998 Dec 11;95(6):817-28
1*	J:297267 Tang Q, Xu M, Xu J, Xie X, Yang H, Gan L, Gfi1-GCE inducible Cre line for hair cell-specific gene manipulation in mouse inner ear. Genesis. 2019 Sep;57(9):e23304
1	J:57339 Thaler J, Harrison K, Sharma K, Lettieri K, Kehrl J, Pfaff SL, Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9. Neuron. 1999 Aug;23(4):675-87
1	J:89755 Thaler JP, Koo SJ, Kania A, Lettieri K, Andrews S, Cox C, Jessell TM, Pfaff SL, A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. Neuron. 2004 Feb 5;41(3):337-50
1*	J:121427 Wang J, Scully K, Zhu X, Cai L, Zhang J, Prefontaine GG, Krones A, Ohgi KA, Zhu P, Garcia-Bassets I, Liu F, Taylor H, Lozach J, Jayes FL, Korach KS, Glass CK, Fu XD, Rosenfeld MG, Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature. 2007 Apr 19;446(7138):882-7
1	J:306250 Wang W, Cho H, Kim D, Park Y, Moon JH, Lim SJ, Yoon SM, McCane M, Aicher SA, Kim S, Emery B, Lee JW, Lee S, Park Y, Lee SK, PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway. Cell Rep. 2020 Sep 15;32(11):108147
1	J:321501 Wang W, Cho H, Lee JW, Lee SK, The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development. Nat Commun. 2022 Feb 17;13(1):958
1	J:130489 Wu Y, Wang G, Scott SA, Capecchi MR, Hoxc10 and Hoxd10 regulate mouse columnar, divisional and motor pool identity of lumbar motoneurons. Development. 2008 Jan;135(1):171-82
1*	J:261409 Xu M, Xie X, Dong X, Liang G, Gan L, Generation and characterization of Lhx3(GFP) reporter knockin and Lhx3(loxP) conditional knockout mice. Genesis. 2018 Apr;56(4):e23098
1*	J:224892 Yan Y, Wladyka C, Fujii J, Sockanathan S, Prdx4 is a compartment-specific H2O2 sensor that regulates neurogenesis by controlling surface expression of GDE2. Nat Commun. 2015;6:7006
1	J:132890 Yip YP, Capriotti C, Drill E, Tsai LH, Yip JW, Cdk5 selectively affects the migration of different populations of neurons in the developing spinal cord. J Comp Neurol. 2007 Jul 10;503(2):297-307
1	J:157264 Zhao Y, Mailloux CM, Hermesz E, Palkovits M, Westphal H, A role of the LIM-homeobox gene Lhx2 in the regulation of pituitary development. Dev Biol. 2010 Jan 15;337(2):313-23